Exponential Wisdom

Episode 121: Mindset Matters

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Peter and Dan discuss having a Longevity Mindset and how that affects all aspects of life. How long you live is a function of many factors, including your mindset. You can actually “Will yourself to death—or will yourself to a longer healthspan.” How long do you think you will live? 80 years old? Maybe, 90? What would have to change for you to believe that you could live to 120 years old?

In this episode:

  • Peter gives evidence of exponential medicine, and why you don’t have to accept the cards you’re dealt. Technologies like genome sequencing, RNA transcriptomics, Wnt pathway modifiers, vaccines, CRISPR, liquid biopsies, CAR-T cells, Gene Therapy, exosomes, and stem cells are just some of the technologies in development.
  • Dan explains when and how he chose the goal of living to 156 years, and how this has shaped his mindset over the years.
  • Peter and Dan agree that many things contribute to a Longevity Mindset, including what you read and watch, your community, your diet and exercise, and ultimately what you believe the future will be like.

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Episode 115: Longevity Tips and Tricks

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Peter and Dan discuss their tips and tricks for a healthy lifestyle, including the importance of mindset, sleep, exercise, and diet.

In this episode:

  • Peter talks about two hacks that help keep his body temperature at an optimum level while sleeping, and how he gamifies getting eight hours every night. 
  • Dan discusses his exercise routine and how he has prioritized muscle mass in his workout routines. 
  • Peter talks about his diet, currently a Mediterranean plant-based diet and fish rich in vitamins, minerals, and antioxidants. Additionally, he uses intermittent fasting between 7pm and 12 noon the next day, providing him a 17-hour fast. It gives him increased energy during the day and helps him.  

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Episode 114: Personalized Health Tracking

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Peter and Dan discuss the many ways in which exponential technologies are extending the healthy human lifespan. Today, we generate and have access to a staggering amount of personalized health data, as personal data-tracking platforms are more accessible and prolific than ever before.

In this episode:

  • Peter touches on his latest book, Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love, co-authored by Dr. Robert Hariri and Tony Robbins, which empowers you to become the CEO of your own health, happiness and vitality through breakthroughs in precision medicine. https://www.lifeforce.com
  • Dan shares the example of one company, InsideTracker, the ultra-personalized nutrition system that analyzes data from your blood, DNA, and habits.
  • Peter discusses how Fountain Life and other companies are building increasingly sophisticated data tracking platforms that empower individuals with personalized health information and a previously inaccessible knowledge base, helping users monitor their own health and act on new insights.

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Episode 108: Giving Yourself Control of Your Health

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Peter and Dan discuss preventive, predictive, and personalized health care. Showcasing this phenomenon, they delve into a new health care company, Fountain Life, which uses data-driven methodologies and thorough diagnostics to identify disease early and enhance members’ physical and mental performance.

In this episode:

  • Peter explains why and how he sees healthcare evolving into a new model, one around which Fountain Life was founded to deliver emerging, best-in-class therapeutics and ground-breaking diagnostics in novel ways to enhance healthspan, performance and vitality.
  • Dan discusses a compelling platform whereby patients can identify new medical therapies and technologies and send corresponding articles or medical papers to Fountain Life’s medical advisory board, by which they can be vetted to determine their viability for the company’s offerings. 
  • Peter expresses that while testing is critical, the most important things we can prioritize are still the basics: sleep, diet and exercise. Peter and Dan give their tips for increasing quality sleep, including a temperature-controlled mattress pad, skipping TV at night, and using audiobooks to help you wind down.

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Episode 92: Longevity Mindset: Part 2

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Peter and Dan continue their conversation about the recent Abundance Platinum Longevity trip, where Peter and a select group of entrepreneurs, executives and investors spent five days learning from the top longevity and immunology experts in two of California’s top biotech hubs.

In this episode:

  • Peter and Dan discuss the explosion of sensors and preventive medicine breakthroughs now emerging at the helm of today’s healthcare market. As smartphone apps and AI more seamlessly enable personalized medicine, consumers will soon be able to monitor and act upon their own health data in real-time.
  • Peter explores his biggest takeaways in the field of CRISPR and genetic engineering. Most notably, Peter showcases Mammoth Biosciences, a pioneering startup on a mission to democratize access to next-generation CRISPR tools for diagnostics and therapeutics. 
  • Peter highlights the importance of cutting out sugar from your diet, a shift critically conducive to improving longevity outcomes. He similarly emphasizes his belief that the biggest contributor to living past 80 is to not die from something stupid.

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Episode 91: Longevity Mindset: Part 1

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Peter and Dan recap the recent Abundance Platinum Longevity trip, where Peter and a select group spent five days learning from the top longevity and immunity experts in two of California’s top biotech hubs.

In this episode:

  • Peter offers his biggest takeaways from the trip, including one insight from Dr. Deepak Srivastava, President of the Gladstone Institutes, who explained why heart disease remains the leading cause of morbidity and mortality in the U.S. A tremendous feat, Dr. Srivastava’s recent discovery involves using gene therapy to convert fibroblasts into heart myocytes, reversing scar tissue in the heart, and helping heart attack victims rapidly recover to live healthy lives. 
  • Dan and Peter agree that mindset is one of the most important pillars of living a long and healthy life. Peter explains why the most important goal is to “not die from something stupid,” as advances in longevity technology will have dramatic impacts on the human healthspan in the next 5-10 years. 
  • Peter talks about the power of intermittent fasting, citing a majority of featured scientists who have touted its health benefits. 

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Episode 88: Cracking the Vitality Code

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Peter and Dan discuss a number of longevity and pharmaceutical companies that are working to crack the vitality code of life. Exponential technologies, from machine learning to CRISPR, are enabling scientists to probe medical data, understand aging, and reverse its processes like never before.

In this episode:

  • Peter discusses a startup he’s tracking that uses gene therapy to treat age and age-related diseases afflicting animals, extending pets’ healthy lifespans by nearly a decade, with no side effects.
  • Dan discusses a major paradigm shift in financial planning, whereby financial advisors that embrace technology are beginning to use forecasts of 120 years instead of conventional actuary tables that take by default a life expectancy of 90 years.
  • Peter and Dan emphasize the importance of a resilient mindset, purpose and long-term inspiration for individuals striving to maximize their longevity journeys.

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Episode 76: Adding 30 Years to Your Healthspan

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With the rise of exponential health technologies, Peter and Dan investigate newly available business opportunities using their “first order implications” framework. When biotech advancements turn sickcare into healthcare, and science adds an additional 20-30 healthy years to our lifespans, what new markets emerge (and which ones disappear)? Peter and Dan discuss the implications to businesses, customers, and society as a whole.

In this episode:

  • Dan delves into the social implications of people having longer professional lives, predicting that mandatory retirement will be moved back by at least 10 years.
  • Peter discusses education industry transformations that will result from people having 2-3 careers. Similarly, once people begin to have far more free time, implications within the travel, tourism, and entertainment industries will unlock new challenges and business opportunities.
  • Peter forecasts our increased food demand over coming decades as people live longer. Consequently, he and Dan project a surge in the lab-grown meat market, which will lead to better-tasting, lower-waste, and far more environmentally sound food production.

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Episode 55: The Immorality of Mortality

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Peter and Dan discuss a recent trip to Vatican City, where the XPRIZE Vision Circle & Innovation Board members met on the annual Adventure Trip to discuss longevity and regenerative medicine, piggybacking on the United to Cure conference hosted by the Pope.

 

In this episode:

  • Peter discusses his opening remarks at the conference with fellow panelists George Church (one of the creators of gene-editing CRISPR technology), Martine Rothblatt (CEO of United Therapeutics, whose goal is to regenerate human organs), and Lou Reese and Mei Mei Hu (co-CEOs of United Neuroscience, focused on creating vaccines against Alzheimer’s and Parkinson’s disease).
  • Dan brings up three keys to longevity: 1) Friends who are progressing, not declining, 2) Enough resources and income to be independent, and 3) Having a purpose, so you look forward to a future that is much greater than the past.
  • Peter and Dan discuss how morality has evolved over time, and how some ideas that were once considered immoral are now considered miracles.

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Episode 47: Retirement the Ultimate Casualty

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Peter and Dan give an update on the latest research in technologies extending the healthy human lifespan.  Peter and Dan agree that “retirement” is one of the leading causes of death, and that mindset is a major factor in the game of human longevity.

 

In this episode:

  • Peter explains how the human race is attacking the three major causes of death — heart disease, cancer, neurodegenerative disease — and why entrepreneurship is a key to this success.
  • Dan explores how the extension of human life will impact Social Security, retirement, and other large programs.
  • Peter and Dan discuss the ‘number in your head’ that dictates when you will die, and how this mindset impacts your health. Dan describes a helpful tool to broaden your thinking and how his Strategic Coach clients have benefited.

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